Recent Faculty Publications and Awards
Dr. Matthew Ferguson recently Co-authored an Article in the EMBO Journal
Entitled “Live-cell imaging reveals the interplay between transcription factors, nucleosomes and bursting”. Benjamin T Donovan, Ann Huynh, David A Ball, Heta P Patel, Michael G Poirier, Daniel R Larson, Matthew L Ferguson, Tineke L Lenstra. DOI: https://doi.org/10.15252/embj.2018100809
Dr. Denise Wingett recently Co-authored an Article in the ACS Journal of Applied Materials & Interfaces
Entitled “Defect Engineering of ZnO Nanoparticles for Bioimaging Applications”. Josh E. Eixenberger, Catherine B. Anders, Katelyn Wada, Kongara M. Reddy, Raquel J. Brown, Jonathan Moreno-Ramirez, Ariel E. Weltner, Chinnathambi Karthik, Dmitri A. Tenne, Daniel Fologea, Denise G. Wingett. DOI: https://doi.org/10.1021/acsami.9b01582 (2019).
Dr. Matthew Ferguson recently Co-authored an Article in The EMBO Journal
Entitled “Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting”. Benjamin T Donovan, Anh Huynh, David A Ball, Heta P Patel, Michael G Poirier, Daniel R Larson, Matthew L Ferguson, Tineke L Lenstra DOI: 10.15252/embj.2018100809
Dr. Ken Cornell Awarded a US Patent
Browning J, Cornell KA. The US Patent is for a Plasma scalpel that is used for selective removal of microbes and microbial biofilms.
Dr. Cheryl Jorcyk Co-authored a Publication in the BMC Journal
OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung. 2018 Jun 14;20(1):53. DOI: 10.1186/s13058-018-0971-5. Tawara K1, Bolin C1, Koncinsky J1, Kadaba S1, Covert H1, Sutherland C1, Bond L1, Kronz J2, Garbow JR3, Jorcyk CL4. Systemic and chronic inflammatory conditions in patients with breast cancer have been associated with reduced patient survival and increased breast cancer aggressiveness.
Dr. Julia Oxford Co-authored a Publication in the Journal of BMC
This paper characterizes the role of an inflammatory cytokine, oncostatin M (OSM), in the preintravasation aspects of breast cancer metastasis. Frahs SM, Oxford JT, Neumann EE, Brown RJ, Keller-Peck CR, Pu X, Lujan TJ. Extracellular Matrix Expression and Production in Fibroblast-Collagen Gels:Towards an In Vitro Model for Ligament Wound Healing. Ann Biomed Eng. 2018 Jun 5. DOI: 10.1007/s10439-018-2064-0. PubMed PMID: 29873012.
Dr. Cheryl Jorcyk and Dr. Julia Oxford Co-authored a Publication in the Journal of PubMed.
DICER1 is a rare genetic disorder that predisposes individuals to multiple cancer types. DICER1 Syndrome: DICER1 Mutations in Rare Cancers. Robertson JC1, Jorcyk CL2,3, Oxford JT4,5 2018 May 15;10(5). pii: E143. DOI: 10.3390/cancers10050143.
Dr. Owen McDougal Co-authored an Article in the New Zealand Journal of Botany
Peter Heenan, Nigel Perry, John van Klink,* NZJ Botany, The article discusses Chemotaxonomy of kōwhai: leaf and seed flavonoids of New Zealand Sophora species. DOI: 10.1080/0028825X.2018.1472107 (2018).
Dr. Owen McDougal and Daniel Pfalmer Co-authored a Publication in BMC Bioinformatics
“SPIDR: small-molecule peptide-influenced drug repurposing” Matthew D. King, Thomas Long, Daniel L. Pfalmer, Timothy L. Andersen, and Owen M. McDougal. DOI: 10.1186/s12859-018-2153-y. Conventional de novo drug design is costly and time consuming, making it accessible to only the best resourced research organizations.
Dr. Cheryl Jorcyk and Dr. Julia Oxford Co-authored a Publication in NCBI Journal
The article discusses a rare genetic disorder that predisposes individuals to multiple cancer type. Robertson JC, Jorcyk CL, Oxford JT. DICER1 Syndrome: DICER1 Mutations in Rare Cancers. Cancers (Basel). 2018 May 15;10(5). PMC – DICER1 Syndrome: DICER1 Mutations in Rare Cancers
Dr. Owen McDougal was Featured in an Article on Boise State News
The article is entitled “Boise State Researchers Helping Idaho Potato Processors Stay Globally Competitive”. It suggests a correlation between acrylamide and a risk of caner. Update – Boise State Researchers Helping Idaho Potato Processors Stay Globally Competitive
Dr. Eric Hayden was Awarded a NASA Grant
This is a three year $661,104 grant from NASA to study how early mutations in ribonucleic acid (RNA) molecules could have given rise to the evolution of life on Earth. Update – Grant to Understand RNA Mutations Could Help Explain Evolution of Life
Dr. Julia Oxford & Dr. Cheryl Jorcyk co-authored a publication in NCBI Journal
It discusses contributing factors to apoptosis and osteoarthritis. Hughes A, Oxford AE, Tawara K, Jorcyk CL, Oxford JT. Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis. Int J Mol Sci. 2017 Mar 20;18(3). To read more follow this link: PubMed – Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology
Dr. Matthew W. Turner and Dr. Owen McDougal Co-authored a Publication in Clinical Toxicology
Mehruba Anwar,† Matthew W. Turner,† Natalija Farrell, Wendy B. Zomlefer, Owen M. McDougal,* Brent W. Morgan,* Clin. Toxicol., “Hikers Poisoned: Identification of Alkaloids in Foraged Veratrum parviflorum.” DOI: 10.1080 15563650.2018.1442007 (2018).
Dr. Denise Wingett Co-authored a Publication in the Royal Society of Chemistry
“ZnO nanoparticle preparation route influences surface reactivity, dissolution and cytotoxicity” Catherine B. Anders, Josh E. Eixenberger, Nevil A. Franco, Rebecca J. Hermann, Katherine D. Rainey, Jordan J. Chess, Alex Punnoose and Denise G. Wingett. DOI: 10.1039/C7EN00888K.
Dr. Daniel Fologea was Awarded a US Patent
Fologea D, Henry R, Salamo G, Mazur Y, Borrelli MJ. Methods and compositions for X-ray induced release from PH sensitive liposomes. Patent No.: 9,849,087 B2. December 26, 2017.
Dr. Ken Cornell Co-authored a Publication in the Journal of Colloid and Interface Science
Urea-derived graphitic carbon nitride (u-g-C3N4) films with highly enhanced antimicrobial and sporicidal activity. Thurston JH, Hunter NM*, Wayment L, Cornell KA (2017) 505: 910-918. PMID 28675870 PMCID: PMC5575986. In this manuscript, we describe the fabrication of photoactive biocidal or sporicidal films from urea-derived graphitic carbon nitride (u-g-C3N4). Co-deposited films of u-g-C3N4 and Escherichia coli O157:H7 (IC50=14.1±0.2mJ) or Staphylococcus aureus (methicillin resistant IC50=33.5±0.2mJ, methicillin sensitive IC50=42.7±0.5mJ) demonstrated significantly enhanced bactericidal behavior upon administration of visible radiation (400nm≤λ≤426nm). PubMed – Urea-derived graphitic carbon nitride (u-g-C3N4) films with highly enhanced antimicrobial and sporicidal activity
Dr. Daniel Fologea Co-authored a Publication in the Journal of Nanobiotechnology
“ZnO nanoparticles modulate the ionic transport and voltage regulation of lysenin nanochannels” Sheenah Bryant, Josh Eixenberger, Steven Rossland, Holly Aspley, Connor Hoffmann, Nisha Shrestha, Michael McHugh, Alex Punnoose, and Daniel Fologea. DOI: 10.1186/s12951-017-0327-9. The insufficient understanding of unintended biological impacts from nanomaterials (NMs) represents a serious impediment to their use for scientific, technological, and medical applications.
Dr. Ken Cornell was Awarded an NIH Grant
This is a three year $417,700 grant from the NIH to develop and test new anti-parasitic drugs to fight Giardia infections. The microscopic parasite Giardia can be found within Idaho, every region of the U.S. and around the world. While Giardia is not considered fatal, anyone who has suffered from the diarrheal disease knows how uncomfortable it can be.
Dr. Eric Hayden was Awarded an NSF Grant
Microbes are invisible and everywhere. They have a significant impact on the environment. This grant is for two years and is $130,772. It will allow research interests to broaden and be brought back to Boise State.
Dr. Eric Hayden Co-authored a Publication in the Journal of Molecular Evolution
“Negative Epistasis in Experimental RNA Fitness Landscapes” Devin P. Bendixsen, Bjorn Ostman, Eric J. Hayden DOI: 10.1007/s00239-017-9817-5. Mutations and their effects on fitness are a fundamental component of evolution. The effects of some mutations change in the presence of other mutations, and this is referred to as epistasis.
Researcher Dr. Daniel Fologea and BMOL Program Featured in the Research Features Magazine
Lysenin channels as single-molecule sensors, controlled nano-valves, and memory elements. This shows studies in the way cells interact with their environment by selective transportation of ions and molecules through the cell membrane.”Lysenin channels“
Dr. Matthew W. Turner and Dr. Owen McDougal Co-authored an Publication in Toxins
“α-Conotoxin Decontamination Protocol Evaluation: What Works and What Doesn’t” Matthew W. Turner, John R. Cort, and Owen M. McDougal. DOI:10.3390/toxins9090281. Nine publically available biosafety protocols for safely handling conotoxin peptides were tested to evaluate their decontamination efficacy.
Dr. Nagarajan Co-authored a Paper in the Proceedings of the National Academy of Sciences
“Molecular basis for the substrate specificity of quorum signal synthases” Dong S.H., Frane N.D., Christensen Q.H., Nagarajan R., Nair S.K. DOI: 10.1073/pnas.1705400114. These first structures of a homoserine-lactone quorum-signal synthase bound to various substrates and analogs help to provide a molecular rationale for understanding acyl chain specificity.
Dr. Matthew Ferguson Awarded NIH Grant to Study How the Genome Works
This $410,000.00 grant is for 3 years. The main focus of the research is how to visualize the splicing and transcription of RNA. It’s rare for a faculty member in any physics department to earn a federal grant administered by the National Institutes of Health (NIH), but that is exactly…
Dr. Denise Wingett Co-authored an Article Published in Chemical Research in Toxicology
“Rapid dissolution of ZnO nanoparticles induced by biological buffers significantly impacts cytotoxicity” Josh Eixenberger, Catherine Anders, Rebecca Hermann, Raquel Brown, K. M. Reddy, Alex Punnoose, and Denise Wingett. DOI:10.1021/acs.chemrestox. 7b00136
Dr. Daniel Fologea Highlighted in Boise State University’s Focus Magazine
“My favorite thing about my job is when students get it, when they understand something and are able to use it,” he said. “It is better than having beautiful food on my plate. It is just the best.” Teaching is the Beautiful Food on His Plate
Dr. Byung Kim Co-authored an Article Published in Smart Materials and Structures
M.H. Korayem, B.I. Kim and A.H. Korayem,“ Experimental and theoretical analysis of the DMASP cantilever vibration behavior based on the MCS theory in moist environment.” Smart Mater. Struct. 27, 075059 (2018). The present study intended to not only increase the accuracy of the simulation with regard to geometric discontinuities based on the Timoshenko beam model using the modified couple stress (MCS) theory … To read more follow this link: Smart Materials and Structures
Dr. Owen McDougal Co-authored an Article Published in Nature Communications
Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death. Decha Pinkaew, Abhijnan Chattopadhyay, Matthew D. King, Preedakorn Chunhacha, Zhihe Liu, Heather L. Stevenson, Yanjie Chen, Patuma Sinthujaroen, Owen M. McDougal & Ken Fujise DOI:10.1038/s41467-017-00029-1. The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is particularly sensitive to stress.
Dr. Owen McDougal Co-authored an Publication in the American Journal of Potato Research
Determination of Glycoalkaloids in Potatoes and Potato Products by Microwave Assisted Extraction. Narasimharao Kondamudi, Jacob K. Smith,† and Owen M. McDougal,* Amer. J. Potato Res., “Determination of Glycoalkaloids in Potatoes and Potato Products by Microwave Assisted Extraction.” 94(2), 153-158 (2017). Scholar Works – Determination of Glycoalkaloids in Potatoes and Potato Products by Microwave Assisted Extraction
Drs. Juliette Tinker and Daniel Fologea Co-authored an Article Published In Scientific Reports
“Stochastic sensing of Angiotensin II with lysenin channels” DOI:10.1038/s41598-017-02438-0
Dr. Matthew Ferguson Awarded National Institute of General Medical Sciences Grant
This $410,174.00 grant is for 3 years to study Spatiotemporal Dynamics of Transcription and Splicing by Two Photon 3D Orbital Tracking.
Dr. Eric Hayden Awarded NASA Grant
This $661,104.00 NASA grant is a renewable 3 year grant to study RNA “Sea-Scapes”: Fitness landscapes with a changing environment (16-EXO16_2-0206).
Dr. Matthew Ferguson is One of IOP Publishing’s Outstanding Reviewer Award Winners for 2016
Dr. Ferguson was awarded this in recognition of the high quality and timeliness of his reviews for Physical Biology. IOP Science
Dr. Allan Albig Co-authored an Article Published in Developmental Biology
LaFoya, B., Munroe, J. A., Mia, M. M., Detweiler, M. A., Crow, J. J., Wood, T., Roth, S., … Albig, A. R. (October 15, 2016). Notch: A multi-functional integrating system of microenvironmental signals. Developmental Biology, 418, 2, 227-241. Europe PMC
Drs. Julie Oxford, Ken Cornell, and Kristen Mitchell Co-authored a Publication in Biomed Research International
Lamb, C. L., Cholico, G. N., Cornell, K. A., Perkins, D. E., Fewkes, M. T., Oxford, J. T., Lujan, T. J., Morrill, E. E., … Mitchell, K. A. (September 28, 2016). Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis. Biomed Research International 2016. PMCID: PMC5079771 NIHMSID: NIHMS820493PMID: 27693115. NCBI
Dr. Daniel Fologea Co-authored an Article Published in Purinergic Signalling
Bryant, S., Shrestha, N., Carnig, P., Kosydar, S., Belzeski, P., Hanna, C., & Fologea, D. (September 18, 2016). Purinergic control of lysenin’s transport and voltage-gating properties. Purinergic Signalling, 12, 3, 549-559. PMCID: PMC5023635 PMID: 27318938. PMC – Purinergic control of lysenin’s transport and voltage-gating properties
Dr. Eric Hayden Authored an Article Published in Methods
Empirical analysis of RNA robustness and evolution using high-throughput sequencing of ribozyme reactions. Methods, Volume 106, 15 August 2016, Pages 97-104, ISSN 1046-2023, Science Direct
Drs. Julie Tinker and Kristen Mitchell Co-authored an Article Published in Biomed Research International
Cheri, L. L., Giovan, N. C., Daniel, E. P., Michael, T. F., Julia, T. O., Trevor, J. L., Erica, E. M., … Kristen, A. M. (August 4, 2016). Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis. Biomed Research International, 2016. PMCID: PMC5031815 PMID: 27672655. Biomed Research International
Dr. Daniel Fologea Co-Authored an Article Published in ACS-Nano Modeling and Analysis of Intercalant Effects on Circular DNA Conformation
Krueger, E., Shim J., Fathizadeh A., Chang A., Subei, A., Yocham K.M., Davis P.H., Graugnard, E., Khalili-Araghi, F., Bashir, R., Estrada, D., and Fologea, D. (2016). ACS-Nano Article DOI: 10.1021/acsnano.6b04876.
Dr. Ken Cornell Co-authored a Paper Published in RSC Advances
Thurston JH, Hunter NM, Cornell KA (2016) Preparation and characterization of photoactive antimicrobial graphitic carbon nitride (g-C3N4) films. RSC Advances, 6(48):42240-42248. NIHMSID: NIHMS782526, PMID 27672437, PMCID PMC5034943. RSC Advances
Drs. Denise Wingett and Alex Punnoose Co-authored a Paper Published in Nanotechnology, Science and Applications
Wingett D, Louka P, Anders C, Zhang J, and Punnoose A.: A role of ZnO nanoparticle electrostatic properties in cancer cell cytotoxicity, Nanotechnology, Science and Applications, 15(9): 29-45, 2016. PMCID: PMC4956064 PMID: 27486313. NSA