{"id":31982,"date":"2016-07-07T13:38:52","date_gmt":"2016-07-07T19:38:52","guid":{"rendered":"https:\/\/brc.boisestate.edu\/?p=31982"},"modified":"2024-11-15T13:22:22","modified_gmt":"2024-11-15T20:22:22","slug":"graphene-flexes-its-muscles-in-boise-state-study","status":"publish","type":"post","link":"https:\/\/www.boisestate.edu\/bri\/2016\/07\/07\/graphene-flexes-its-muscles-in-boise-state-study\/","title":{"rendered":"Graphene Flexes its Muscles in Boise State Study"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A team of researchers from Boise State University, led by Eric Krueger and David Estrada, have published an article in the American Chemical Society\u2019s Biomaterials Science and Engineering journal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Titled \u201cGraphene Foam as a 3-dimensional Platform for Myotube Growth,\u201d it focuses on a study demonstrating the suitability of graphene foam as a scaffold for growing functional muscle tissue. Graphene foam is an emerging 3D version of graphene, a layer of carbon so thin it is considered 2-dimensional.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ultimately, researchers hope that the unique properties of graphene and graphene foam can be used to regenerate 3-dimensional tissues and organs for implantation into the human body. Past studies have confirmed bone and cartilage growth on graphene foam, but this is the first known study of its compatibility with muscle growth.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cNot only did we demonstrate that extra cellular matrix proteins on graphene foam can enhance the differentiation of pluripotent C2C12 myoblasts, but we were able to verify muscle functionality by using the graphene foam itself as an electrode to stimulate the tissue,\u201d said Krueger, postdoctoral research associate in the Micron School of Materials Science and Engineering. \u201cYou can actually see the movement of the cells and graphene foam as the muscle cells contract.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The extracellular matrix consists of molecules secreted by cells within the connective tissues and organs of the body. Differentiation of pluripotent cells in response to their local environment is an area of intense research effort, and one that can make a significant impact to biomedical research and the treatment of connective tissue diseases through a regenerative medicine approach.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study was a collaboration between three Boise State Ph.D. programs \u2014 in biomolecular sciences, electrical and computer engineering, and materials science and engineering \u2014 and used resources made available through the Biomolecular Research Center (BRC). The BRC is funded by a NIH Center of Biomedical Research Excellence (COBRE) in matrix biology award.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThis publication demonstrates the progress that can be made through collaboration based on a team approach to scientific research \u2014 this is the best way to accomplish such progress, and precisely the type of multidisciplinary project that the Biomolecular Research Center is established to support,\u201d said center director Julia Oxford, a distinguished professor, program director and principal investigator of the COBRE award.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cThese results help shed light on graphene\u2019s ability to artificially engineer the chief components of the musculoskeletal system, which could have a major impact on understanding a variety of musculoskeletal disorders,\u201d said assistant professor Estrada, coordinator of Boise State\u2019s materials science and engineering graduate program and corresponding author on the paper.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Developing new bioscaffolds for tissue engineering, particular 3D scaffolds, will help advance our understanding of stem cell behavior in three-dimensional microenvironments. Such understanding could allow engineers and scientists to control the 3-dimensional growth and differentiation of stem cells in order to engineer biological systems.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Now, the group is working to exploit the full spectrum of graphene\u2019s unique properties for tissue engineering.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cWe think we can build on these results to investigate the fundamental chemistry of life while advancing towards clinical applications,\u201d Estrada said. \u201cGraphene has just begun to flex its muscles in the bioengineering domain.\u201d<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"155\" src=\"https:\/\/www.boisestate.edu\/bri\/wp-content\/uploads\/sites\/147\/2016\/07\/Graphene-1-300x155.jpg\" alt=\"microscope image\" class=\"wp-image-31992\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Raquel Brown: Confocal fluorescence microscope image of C2C12 myoblasts on graphene foam.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Authors are:<br>\nEric Krueger (now at Lehigh University), Materials Science and Engineering<br>\nNicole Chang, Materials Science and Engineering<br>\nDale Brown, Materials Science and Engineering<br>\nJosh Eixenberger, Physics, Biomolecular Research Center, Biomolecular Sciences Ph.D. program<br>\nRaquel Brown, Biomolecular Research Center<br>\nSepideh Rastegar, Electrical and Computer Engineering<br>\nKatie Yocham, Mechanical and Biomedical Engineering<br>\nKurtis Cantley, Electrical and Computer Engineering<br>\nDavid Estrada, Materials Science and Engineering<br>\nAdditional funding was provided by: Idaho INBRE Program, J. Murdock Charitable Trust, The National Science Foundation, The Idaho State Board of Education and Lori and Duane Stueckle<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Article By: Sherry Squires<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers from Boise State University, led by Eric Krueger and David Estrada,&#8230;<\/p>\n","protected":false},"author":108,"featured_media":31992,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[7],"tags":[],"class_list":["post-31982","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Graphene Flexes its Muscles in Boise State Study - Biomedical Research Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.boisestate.edu\/bri\/2016\/07\/07\/graphene-flexes-its-muscles-in-boise-state-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Graphene Flexes its Muscles in Boise State Study\" \/>\n<meta property=\"og:description\" content=\"A team of researchers from Boise State University, led by Eric Krueger and David Estrada,...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.boisestate.edu\/bri\/2016\/07\/07\/graphene-flexes-its-muscles-in-boise-state-study\/\" \/>\n<meta property=\"og:site_name\" content=\"Biomedical Research Institute\" \/>\n<meta property=\"article:published_time\" content=\"2016-07-07T19:38:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-15T20:22:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.boisestate.edu\/bri\/wp-content\/uploads\/sites\/147\/2016\/07\/Graphene-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"320\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"tracyyarnell\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"tracyyarnell\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/\"},\"author\":{\"name\":\"tracyyarnell\",\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/#\\\/schema\\\/person\\\/60d47ec2470e1ca23a4eaf20831a289c\"},\"headline\":\"Graphene Flexes its Muscles in Boise State Study\",\"datePublished\":\"2016-07-07T19:38:52+00:00\",\"dateModified\":\"2024-11-15T20:22:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/\"},\"wordCount\":639,\"image\":{\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/wp-content\\\/uploads\\\/sites\\\/147\\\/2016\\\/07\\\/Graphene-1.jpg\",\"articleSection\":[\"BRC News Posts\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/\",\"url\":\"https:\\\/\\\/www.boisestate.edu\\\/bri\\\/2016\\\/07\\\/07\\\/graphene-flexes-its-muscles-in-boise-state-study\\\/\",\"name\":\"Graphene Flexes its Muscles in Boise State Study - 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