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Owen McDougal

Chemistry Department Chair and Professor Owen McDougal, with biomolecular sciences doctoral candidate Matthew Turner and chemistry graduate students Paul Phillips and Leanna Marquart, co-authored a recently published article in the open access journal Toxins.

Owen McDougal and collaborating student authors
From left: Matt Turner, Leanna Marquart, Paul Phillips and Owen McDougal

An excerpt from the abstract begins: “Nicotinicacetylcholine receptors (nAChRs) are found throughout the mammalian body and have been studied extensively because of their implication in a myriad of diseases. α-Conotoxins (α-CTxs) are peptide neurotoxins found in the venom of marine snails of genus Conus. α-CTxs are potent and selective antagonists for a variety of nAChR isoforms.”

To read the article, click here: Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors