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Limited Submission Notice: IDeA Clinical & Translational Research Development (CTR-D) Award (P20-Clinical Trial Optional) — PAR-23-257


National Institutes of Health (NIH)


The IDeA Clinical & Translational Research programs build clinical and translational (C&T) research capacity to enable research on diseases and health challenges prevalent in IDeA states. This Notice of Funding Opportunity (NOFO) supports IDeA Clinical and Translational Research Development (CTR-D) awards that focus on C&T research workforce development and infrastructure enhancement at health research organizations in IDeA-eligible states that have limited clinical research capacity. To maximize the impact of the capacity building investment, an organization may participate in only one CTR-D, CTR-N, or IDeA-CTR award at a time; see Section III. Eligibility Information for details. Additionally, an organization may only receive funding from one CTR-D. In keeping with the goals of the CTR-D program, applications with a narrow disease or population focus will not be accepted for review.

For more information, please view the full PAR-23-257 solicitation.


$1.5 million in annual direct costs (excluding F&A costs) for a maximum of five (5) years.

Limited Submission Requirements and Timeline:

=Only one (1) application per institution is permitted.

Only proposals approved by the Division of Research and Economic Development may be submitted to this program. For such approval, Principal Investigators (PIs) must first submit a Notice of Interest to by 3 PM on September 7, 2023. An additional white paper round may be conducted if necessary.

If selected to submit a full proposal, PIs must ensure that proposals meet all requirements stated in the RFP, in the announcement, and in the implementing laws and regulations related to this grant program.

Key Submission Dates:

  • 9/7/2023, by 3 PM – Email indicating interest due to We encourage you to cc your Dean for visibility as well.
  • [possible White Paper competition, if necessary]
  • 11/02/2023 – Full proposal due to OSP.
  • 11/09/2023 – Full proposal due to NIH.

Important Note on Requirements:

Applicants to this NOFO are expected to be health research organizations committed to CTR-D’s goal of developing C&T research capacity. Applicant organizations are encouraged to partner with other eligible health research organizations or healthcare delivery organizations that desire to engage in clinical research. Applicant organizations should have a well-established research administration infrastructure that can effectively manage C&T research projects and potentially administer sub-awards made to other organizations. CTR-D partner organizations must substantively participate in CTR-D activities and contribute to the program’s mission. CTR-D programs are encouraged to work with community clinics, such as those of the Practice-Based Research Network (PBRN), with the goal of engaging their clinical staff and patients in research.

An established investigator, or investigators for multiple PD/PI (multi-PI) applications, with a track record of external funding in C&T research is expected to lead the CTR-D program as the Program Director/Principal Investigator (PD/PI). The PD(s)/PI(s) should also have the leadership experience to work across organizational boundaries and to have mentoring experience in fostering the development of a C&T research workforce.

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